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Hemoglobinopothies

Real mutations; real people

Mutations marked 'not ready' lack supporting display elements. Make sure to consider and compare both the oxy and deoxy conformation; rotation (drag the image) may be required for the best view, and the 'cutaway' checkbox may help. Lightly colored amino acids are important neighbors highlighted for your consideration.

  

Oxygen is shown as cyan; heme is green

alpha chain

beta chain