Oxygen: brought to you by proteins
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Together and apart
The ties that bind
Hemoglobins two states (conformations) each contain interactions that help hold them together. Some interactions are common to both of them; others occur only in one or the other.
alpha Lys40 + beta His146
deoxy
oxy
alpha Tyr42 + beta Asp99
deoxy
oxy
alpha Val93 + (same) alpha Tyr140
deoxy
oxy
alpha Asp94 + beta Asn102
deoxy
oxy
beta Asp94 + (same) beta His146
deoxy
oxy
alpha Asp126 + (other) alpha Arg141
deoxy
oxy
alpha Lys127 + (other) alpha Arg141
deoxy
oxy