What it is

BasePairer (click the cap above for a teaser movie) is an interactive web app that allows students to assign 'feels' (H-bond donor/acceptor partial charges) to basepairing positions on 3D nucleotides and then to explore how bases interact by orienting them relative to one another. Tautomers and deaminations can also be investigated. Thoughts on key concepts re: DNA

Instructions

Walk through of basic operations (apply to the older, working version; newer version is 'push buttons and see what happens' for now)

Web BasePairer

BasePairer is now an HTML5 app in jsMOL. Icon above links to the current version; use the airplane icon in the rightward hex for the older app that has some additional features.

Launch older version

The original, (still has more bells and whistles) version; plays using the Adobe Shockwave plugin. Access by clicking the icon above.

worksheet, rubric

Click the icon above to for a directory of worksheets and rubrics. Note that BasePairer can be used to examine the 'offsets' used in 'Wobble' pairing as seen in codon:anticodon interaction, and first laid out in a 'Basepairer-like' paper by Crick.

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